Which principle is most closely associated with the concept of respect for persons in research ethics?

The principle most closely associated with the concept of respect for persons in research ethics is informed consent. This principle emphasizes the need to recognize and uphold the autonomy of individuals participating in research. Informed consent requires that participants are fully informed about the nature of the study, the risks and benefits involved, and their right to withdraw at any time without penalty. This process is crucial as it allows individuals to make knowledgeable decisions about their participation, reflecting their personal values and preferences.

Respect for persons is a foundational ethical principle that acknowledges the dignity and worth of each individual. It focuses on treating people as autonomous agents and protecting those with diminished autonomy. Informed consent is a practical application of this respect, ensuring that participants are not merely subjects but active contributors to the research process with their rights upheld.

While confidentiality of data, justice in recruitment practices, and data integrity are important ethical considerations, they do not directly encapsulate the principle of respect for persons in the same way informed consent does. For instance, confidentiality protects participants' private information, but it does not address their right to make an autonomous decision regarding their participation. Similarly, justice in recruitment practices relates to fairness in selecting research subjects, and data integrity concerns accuracy in the research process, but neither specifically highlights the autonomy and