Which of the following is a requirement for institutions seeking HHS funding?

Institutions seeking funding from the Department of Health and Human Services (HHS) must fulfill specific requirements to ensure compliance with federal regulations regarding human subjects research. One key requirement is the obligation to report to federal funding agencies when necessary. This includes updating funding agencies on significant developments, adverse events, or changes in the research that might pertain to the assurance of human subjects' safety and rights.

This reporting is essential as it helps maintain transparency and accountability within research projects, ensuring that appropriate measures are taken to protect human participants throughout the study. Adhering to this requirement not only fulfills institutional obligations but also fosters trust between researchers, funding agencies, and the communities involved in the research.

In contrast, while obtaining state approval and completing training for all participants can be important aspects of conducting research, they are not universally mandated for HHS funding. Likewise, drafting a research manuscript prior to seeking Institutional Review Board (IRB) approval is not a standard requirement; rather, IRB approval is needed before any research involving human subjects can commence, regardless of any manuscripts.