How often is continuing review required for expedited research under certain circumstances according to the IRB?

The frequency of continuing review for expedited research is determined by the Institutional Review Board (IRB) based on the specific circumstances of the study. This flexibility allows the IRB to tailor the review frequency to the nature of the research, the associated risks, and the overall context of the study. For example, if the research involves minimal risk or if there are no significant changes to the study protocol, the IRB may decide that less frequent reviews are appropriate. Conversely, if there are emerging concerns or changes that could impact participant safety or data integrity, the IRB could require more frequent reviews. This approach emphasizes the IRB's role in overseeing research ethics and participant protection in a way that is responsive to the specific details of each study.