According to federal law, is compliance with the Common Rule mandatory for all research conducted in the U.S.?

The assertion that compliance with the Common Rule depends on the research type reflects the fact that the Common Rule primarily governs research involving human subjects that is conducted or supported by federal departments and agencies. The federal regulations set forth specific criteria that must be met to ensure the ethical treatment of human subjects.

Certain types of research, such as privately funded studies or certain types of institutional research, may not fall under the jurisdiction of the Common Rule and may follow different ethical guidelines or institutional policies instead. For instance, research conducted solely within a private company that does not involve federal funding may not be subject to the requirements of the Common Rule, but it is still bound by other ethical standards and regulations that may apply.

This understanding highlights the nuances of regulatory compliance in human subject research, where the source of funding and the nature of the research can influence the applicable ethical guidelines.